The HAND2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to HAND2. This antibody recognizes Human antigen. The HAND2 Antibody has been validated for the following applications: ELISA, and Immunohistochemistry.
Description
Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3' (By similarity)